MuSIC (Multi-Species RBP–RNA Interactions using Conservation) a deep learning framework for predicting RBP–RNA interactions across multiple species, leveraging both RNA sequence and structure features, and evolutionary conservation.
Reference
He, J., Zhou, T., Hu, L.-F., Jiao, Y., Wang, J., Yan, S., Jia, S., Chen, Q., Zhu, W., Zhang, J., Jia, M., Li, Y., Wang, X., Wang, Y., Yang, Y.T., and Sun, L. (2026). Augmented prediction of multi-species protein-RNA interactions using evolutionary conservation of RNA-binding proteins. Nature Communications 17 , 5764 (2026). https://doi.org/10.1038/s41467-026-72351-6
If you want to make predictions across cell lines, you can use PrismNet .